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Research &
Development

Code Pharma is well positioned to play a key role in the current race to develop a cure for HIV. Our drug Gammora - which was originally discovered at the Hebrew University in Israel - has a very good safety profile and very impressive activity in HIV, both under laboratory conditions and in our clinical trials.

Gammora eliminates the HIV infected cells in difference from the cocktail drugs used today which works on the virus itself.

Clinical studies

Gammora is a short synthetic peptide derived from HIV virus that was found in preclinical and clinical examinations to either:

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1. Promote HIV-infected cells into self-induced death (apoptosis), and Lentivirus     manipulation in the case of cancer therapy.

2. Leads to antiviral effect against RNA viruses.

Pipeline

Phase 1 clinical trial - Completed
A subsequent phase I clinical trial of Codivir in patients with COVID-19, approved by Brazil’s National Research Ethics Commission (CONEP) and conducted at Vera Cruz Hospital in São Paulo, Brazil, demonstrated a high safety profile while significantly suppressing viral replication in most of the fully assessed patients with an antiviral effect noted as early as three days. All patients recovered quickly after the treatment with Codivir and didn’t show any signs of side effects very often associated with COVID-19 infections. 


Phase 2a clinical trial – Ongoing

Following the successful safety results of phase I study, the company is conducting a phase IIa randomized open label controlled study in Brazil, in HIV patients. Along with safety results, this study can indicate proof of concept for the drug efficacy in HIV patients.

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Code Pharma has already received emergency approvals from several countries and is preparing for mass production of Gammora in different production sites worldwide based on the received orders.

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